Activated vitamins are in a form that is readily available to be utilised by the body as a substrate in biochemical reactions immediately following ingestion. This means that they do not have to be broken down and manufactured by the body into a usable form as is the case with the inactive vitamins. This is beneficial if there is a problem with the process of digestion or if some enzymatic functions are lacking in some way.
Activated vitamins are important co-factors in many body processes and they are also great for kids or older patients.
The active forms of Riboflavin are synthesised in the mitochondria, forming Riboflavin-5-Phosphate which is then converted further to Flavine Adenine Dinucleotide (FAD).
Metabolics Vitamin B2 is in its bioavailable form Riboflavin-5-phosphate.
Metabolics products are manufactured under strict guidelines of GMP and HACCP certification and are ISO:9001and ISO:14001 accredited. Registered with US Food and Drug Administration but not TGA approved. GMP = Good Manufacturing Practices
Action of product:
- Regulates thyroid activity, however conversely needs thyroid hormones to be activated. This means that any hypothyroid issues may require B2 supplementation to support thyroid health and healthy metabolism.
- Active B2 is an essential cofactor to monoaminoxidase (MOA) which breaks down serotonin which can help to reduce migraines caused by excess serotonin. MAO also breaks down noradrenaline and histamine, thus reducing inflammation, which B2 can assist with.
- Energy Production: Vitamin B2 is a key component of the Krebs cycle and production of ATP, thus a lack of active B2 can affect energy production and cause an increase in fatty acids which can lead to cholesterol imbalance.
- Cellular Health: Vitamin B2 supports the health of cells and tissues, playing a role in growth, development, and maintenance as well as growth of the foetus in utero. Therefore good for pregnancy.
- Eye Health: Vitamin B2 plays a role in maintaining healthy vision and protecting the eyes from oxidative stress. Eyelid twitching often indicates the need for B2 supplementation
- Skin, mouth and hair health: Dermatitis with dryness and greasy scaling, seborrhoeic dermatitis, cracks and sores on lips and cracks in the corners of the mouth, geographic tongue and genital lesions are all an indication of B2 deficiency.
- Nervous System Support: Vitamin B2 is an important cofactor in activation of B6 and folate, and supports the health and function of the nervous system, contributing to proper nerve signalling and neurotransmitter synthesis. Useful for stroke and traumatic brain injury (TBI).
Characteristic of active B2 deficiency: cracks in the corner of the mouth, thyroid problems, eyelid twitching, low Vitamin B6 symptoms.
Store at room temperature below 25o C. Refrigerate after opening. Consume within 3 months of opening.
Purified Water, Riboflavin 5 Phosphate, Citric acid.
Vegetarian, vegan, gluten free, nut free, preservative free, dairy free, alcohol free, without binders, fillers and flowing agents.
250 ml, 500 ml, 500ml 01/24 Expiry (end of month), 500ml 11/23 Expiry (end of month)
For extemporaneous dispensing in a clinical setting as directed by a health care practitioner. Due to the high bioavailability of the product, the dosages are more conservative than non-activated supplements.
Adult: 2mg= 1 serving = 12 drops, 115 servings per 100ml
Children (6-12yrs): 1mg = 1 serving = 6 drops
Children (2-6yrs): 320mcg = 1 serving = 2 drops
Children (0-2yrs): 160mcg = 1 serving = 1 drop
Empty 50ml, 25ml and 15ml dropper bottles can be purchased from PHS.
|Cautions/Contraindications (if applicable)
While Vitamin B2, specifically Riboflavin-5-Phosphate, is generally safe and well-tolerated, there are a few cautions and contraindications to be aware of:
Allergies: Some individuals may be allergic to Vitamin B2 or other components present in supplements containing Riboflavin-5-Phosphate. If you have a known allergy to Vitamin B2 or experience allergic reactions such as rash, itching, or swelling, it is important to avoid its use.
Certain Medical Conditions: Individuals with specific medical conditions should exercise caution. These conditions include liver diseases, gallbladder disorders, and genetic disorders such as glucose-6-phosphate dehydrogenase deficiency.
Interactions with Medications: Riboflavin-5-Phosphate may interact with certain medications, such as tricyclic antidepressants, phenothiazines, and certain antimalarial drugs. It is important to inform your healthcare provider about all the medications, including over-the-counter and herbal supplements, you are taking to avoid potential interactions.
Pregnancy and Breastfeeding: Riboflavin-5-Phosphate is generally considered safe for use during pregnancy and breastfeeding when taken at recommended doses. However, it is always advisable to consult with a healthcare professional before starting any supplementation during these periods.